Abstract: An alternative method was studied for catalytically reductive hydrodechlorinatio n and mono-N-alkylation of 2-chloro-4,6-dinitrobenzene-1,3-diol, an i nexpensive material, to synthesize corresponding N-alkyl secondary aminophe nol, 4,6-bis(isopropylamino)benzene-1,3-diol, at a high yield by using aceton e as the alkyl source and hydrogen as the reducing reagent over 10%Pd/C catalyst .

Key words: one-pot reductive mono-N-alkylation, hydrodechlorination, 2-chloro-4, 6-dinitrobenzene-1, 3-diol, 4, 6-bis(isopropylamino)benzene-1, 3-diol