Chinese Journal of Catalysis ›› 2008, Vol. 29 ›› Issue (10): 997-1002.

• Articles • Previous Articles     Next Articles

Screening of Lactonase-Producing Strains and Their Performance in Catalytic Resolution of Chiral Lactones

ZHANG Xian, PAN Jiang, XU Jianhe*   

  1. State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China
  • Received:2008-10-25 Online:2008-10-25 Published:2008-10-25

Abstract: By using immobilized cells of Fusarium proliferatum ECU2002, which was new ly isolated from soil samples, biocatalytic resolution of (±)-α-hydroxy-γ -butyrolactone was performed at a concentration of 1 mol/L and repeated for 10 cycles of reaction, retaining 92.8% of initial activity and affording the produc t with 92.8%-96.1% ee.

Key words: lactonase, Fusarium moniliforme ECU2001, Fusarium proliferatum ECU2002, immobilized cell, &alpha, -hydroxy-&gamma, -butyrolactone