Relationship between Catalytic Asymmetric Reduction Ability of Carbonyl Reductase of Rhodobacter sphaeroides and Substrate Structure

Chinese Journal of Catalysis ›› 2010, Vol. 31 ›› Issue (2): 195-199.

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Relationship between Catalytic Asymmetric Reduction Ability of Carbonyl Reductase of Rhodobacter sphaeroides and Substrate Structure

WANG Mengliang*, YAN Fukun

Institute of Applied Chemistry, Shanxi University, Taiyuan 030006, Shanxi, China

Received:2010-02-25 Online:2010-02-25 Published:2013-09-02

Abstract

Abstract: Based on the asymmetric reduction of latent chiral ketones by whole cells or carbonyl reductase of Rhodobacter sphaeroides, the relationship between the catalytic ability of Rhodobacter sphaeroides and the structure of substrates was studied.

Key words: Rhodobacter sphaeroides, biocatalysis, carbonyl reductase, acetophenone, derivative, aliphatic ketone, structure-activity relationship

WANG Mengliang*;YAN Fukun. Relationship between Catalytic Asymmetric Reduction Ability of Carbonyl Reductase of Rhodobacter sphaeroides and Substrate Structure[J]. Chinese Journal of Catalysis, 2010, 31(2): 195-199.

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Relationship between Catalytic Asymmetric Reduction Ability of Carbonyl Reductase of Rhodobacter sphaeroides and Substrate Structure

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