Chinese Journal of Catalysis ›› 2015, Vol. 36 ›› Issue (8): 1387-1391.DOI: 10.1016/S1872-2067(15)60843-9

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Easily prepared water soluble Pd-NHC complex as an efficient, phosphine-free palladium catalyst for the Sonogashira reaction

Chunyan Zhanga,b, Jianhua Liua, Chungu Xiaa   

  1. a State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, Gansu, China;
    b University of Chinese Academy of Sciences, Beijing 100039, China
  • Received:2015-02-23 Revised:2015-03-09 Online:2015-07-29 Published:2015-07-30
  • Supported by:

    This work was supported by the National Natural Science Foundation of China (21373248 and 21133011).

Abstract:

A water soluble Pd-NHC complex was prepared and its catalytic activity in the Sonogashira reaction of terminal alkynes and aryl iodides using water as solvent under phosphine-free conditions was shown. This gives an efficient approach to diarylalkynes. The water soluble Pd-NHC complex can be easily recovered by extraction of the reaction solution and it was reused four times with only a slight loss of catalytic activity.

Key words: Pd-NHC complex, Sonogashira reaction, Water, Aryl iodide, Terminal alkyne