Fig. 1. Scheme of artificial starch anabolic pathway. Inner circle: schematic of the artificial starch pathway drafted by computational pathway design with divided modules. C1 here indicates formic acid and methanol. Outer circle: schematic of artificial starch anabolic pathway (ASAP) 1.0, with individual modules colored. Auxiliary enzymes and chemicals are indicated. ADPG, ADP glucose; aox, alcohol oxidase; FADH, formaldehyde; F-1,6-BP, D-fructose-1,6-bisphosphate; F-6-P, D-fructose-6- phosphate; GAP, D-glyceraldehyde 3-phosphate; pgi, phosphoglucose isomerase; polyP, polyphosphate; pgm, phosphoglucomutase; ppa, pyrophosphatase; ppk, polyphosphate kinase; ss, starch synthase; tpi, triosephosphate isomerase. Reprinted with permission from Ref. [2]. Copyright 2021, Science.