]*>","")" /> 二茂铁衍生的手性硫膦配体在铱催化喹啉不对称氢化中的应用
催化学报

催化学报 ›› 2005, Vol. 26 ›› Issue (9): 737-739.

• 研究快讯 • 上一篇    下一篇

二茂铁衍生的手性硫膦配体在铱催化喹啉不对称氢化中的应用

赵玉军,汪游清,周永贵   

  1. 中国科学院大连化学物理研究所, 辽宁大连 116023
  • 收稿日期:2005-09-25 出版日期:2005-09-25 发布日期:1985-12-26

  • Received:2005-09-25 Online:2005-09-25 Published:1985-12-26

PDF

787

被引次数

19

摘要： Chiral S,P-donor ferrocene-derived ligands were synthesized and applied in the asymmetric hydrogenation of quinolines using the ［Ir(COD)Cl］2/S,P-ligand complex as the catalyst in the presence of iodine. The effects of the solvent and hydrogen pressure on conversion and enantioselectivity were examined, and up to 82% ee was obtained. The planar chirality plays an important role in this reaction. R- and S-enantiomers of 1,2,3,4-tetrahydroquinoline derivatives were obtained using ligands 3 and 5, respectively.

关键词: 二茂铁, 手性硫膦配体, 铱, 喹啉, 不对称氢化