催化学报

催化学报 ›› 2006, Vol. 27 ›› Issue (3): 197-199.

• 研究快讯 • 上一篇    下一篇

氯铝酸离子液体中Glyoxylate-Ene反应合成α-羟基酯

沈振陆,何锡君,莫卫民,谢翼,胡宝祥,孙楠   

  1. 浙江工业大学化学工程与材料学院, 浙江杭州 310032
  • 收稿日期:2006-03-25 出版日期:2006-03-25 发布日期:1984-10-26

Synthesis of α-Hydroxy Esters by Glyoxylate-Ene Reaction in Lewis Acid Chloroaluminate Ionic Liquids

SHEN Zhenlu*, HE Xijun, MO Weimin, XIE Yi, HU Baoxiang, SUN Nan   

  1. College of Chemical Engineering and Material Science, Zhejiang University of Technology, Hangzhou 310032, Zhejiang, China
  • Received:2006-03-25 Online:2006-03-25 Published:1984-10-26

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摘要： The chloroaluminate ionic liquid, composed of AlCl3 and 1-butyl-3-methylimidazolium chloride (［bmim］Cl), is used as the solvent and catalyst to synthesize α-hydroxy esters from alkene and glyoxylate via the glyoxylate-ene reaction. Under the reaction conditions of 15 ℃, 4 h, and AlCl3/［bmim］Cl molar ratio of 2, the ethyl α-hydroxy-4-phenyl-4-pentenoate with high yield (95.2%) is obtained in the reaction of α-methyl styrene and ethyl glyoxylate. Other α-hydroxy esters can also be obtained in high yields through the glyoxylate-ene reaction. Moreover, the chloroaluminate ionic liquid can be reused several times.

关键词: glyoxylate-ene反应, 离子液体, &alpha, -羟基酯, 氯化铝, 乙醛酸酯

Abstract: The chloroaluminate ionic liquid, composed of AlCl3 and 1-butyl-3-methylimidazolium chloride (［bmim］Cl), is used as the solvent and catalyst to synthesize α-hydroxy esters from alkene and glyoxylate via the glyoxylate-ene reaction. Under the reaction conditions of 15 ℃, 4 h, and AlCl3/［bmim］Cl molar ratio of 2, the ethyl α-hydroxy-4-phenyl-4-pentenoate with high yield (95.2%) is obtained in the reaction of α-methyl styrene and ethyl glyoxylate. Other α-hydroxy esters can also be obtained in high yields through the glyoxylate-ene reaction. Moreover, the chloroaluminate ionic liquid can be reused several times.

Key words: glyoxylate-ene reaction, ionic liquid, α-hydroxy ester, aluminium chloride, glyoxylate