催化学报

催化学报 ›› 2007, Vol. 28 ›› Issue (11): 934-936.

• 研究快讯 • 上一篇    下一篇

铜络合物催化β-(-)-蒎烯的不对称环丙烷化反应

李争宁1,姜岚1,刘改玲1,陈惠麟2   

  1. 1 大连大学环境与化工学院, 辽宁省生物有机化学重点实验室, 辽宁大连 116622; 2 中国科学院大连化学物理研究所, 辽宁大连 116023
  • 收稿日期:2007-11-25 出版日期:2007-11-25 发布日期:2011-10-13

Asymmetric Cyclopropanation of β-(-)-Pinene Catalyzed by Copper Complexes

LI Zhengning1*, JIANG Lan1, LIU Gailing1, CHEN Huilin2   

  1. 1 Liaoning Key Laboratory of Bioorganic Chemistry, College of Environmental and Chemical Engineering, Dalian University, Dalian 116622, Liaoning, China; 2 Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian 116023, Liaoning, China
  • Received:2007-11-25 Online:2007-11-25 Published:2011-10-13

PDF

1022

被引次数

7

摘要： 分别用水杨醛铜、β-二酮-铜和希夫碱-铜络合物为催化剂进行β-(-)-蒎烯与重氮乙酸酯的不对称环丙烷化反应,研究了催化剂结构与反应立体选择性之间的关系,获得了较高的立体选择性.

关键词: 环丙烷化, 立体选择性, 铜络合物, β-(-)-蒎烯, 重氮乙酸酯

Abstract: The asymmetric cyclopropanation of β-(-)-pinene with diazoacetate was performed in the presence of copper salicylaldehydate, copper diketonates, and copper-Schiff base complexes as the catalyst, respectively. The relationship between the stereoselectivity for the reaction and structure of the copper-Schiff base was studied, and high stereoselectivity was achieved.

Key words: cyclopropanation, stereoselectivity, copper complex, β-(-)-pinene, diazoacetate