催化学报

催化学报 ›› 2010, Vol. 31 ›› Issue (3): 273-277.

• 研究论文 • 上一篇    下一篇

水相中RuCl2(TPPTS)2-(S,S)-DPENDS催化苄叉丙酮的不对称加氢反应

王金波1, 秦瑞香1, 熊伟1, 贾云1, 刘德蓉1, 冯建1, 陈华2   

  1. 1 重庆科技学院化学化工学院, 重庆 401331 2 四川大学化学学院绿色化学及技术教育部重点实验室, 四川成都 610064
  • 收稿日期:2010-03-25 出版日期:2010-03-25 发布日期:2010-03-25

Asymmetric Hydrogenation of Benzalacetone Catalyzed by RuCl2(TPPTS)2-(S,S)-DPENDS in Water Medium

WANG Jinbo1, QIN Ruixiang1, XIONG Wei1, JIA Yun1, LIU Derong1, FENG Jian1, CHEN Hua2,*   

  1. 1College of Chemistry and Chemical Engineering, Chongqing College of Science and Technology, Chongqing 401331, China 2Key Labora-tory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, Sichuan, China
  • Received:2010-03-25 Online:2010-03-25 Published:2010-03-25

PDF

1142

被引次数

23

摘要： 将水溶性手性二胺 (S,S)-1,2-二苯基乙二胺二磺酸钠 ((S,S)-DPENDS) 与钌膦配合物 ([RuCl2(TPPTS)2]2) 原位生成的催化剂用于催化水相中苄叉丙酮的不对称加氢反应. 在优化条件下, 羰基加氢产物 4-苯基-3-丁烯-2-醇的选择性可达 96.0%, 对映选择性可达 71.2%. 经正己烷简单萃取后即可实现催化剂与加氢产物的分离, 循环使用 5 次后, 目标产物 4-苯基-3-丁烯-2-醇选择性和对映选择性没有明显下降.

关键词: 钌膦配合物, 苄叉丙酮, 水相, 不对称加氢, 对映选择性

Abstract: The asymmetric hydrogenation of benzalacetone catalyzed by RuCl2(TPPTS)2-(S,S)-DPENDS in water medium was investigated. The selectivity of 96.0% for 4-phenyl-3-butene-2-ol and ee value of 71.2% were obtained. The catalyst could be reused five times without evident loss of catalytic activity and enantioselectivity.

Key words: ruthenium monophosphine complex, benzalacetone, water medium, asymmetric hydrogenation, enantioselectivity