Solvent-Free Selective Cross-Aldol Condensation of Ketones with Aromatic Aldehydes Efficiently Catalyzed by a Reusable Supported Acidic Ionic Liquid

doi:10.1016/S1872-2067(11)60470-1

催化学报 ›› 2012, Vol. 33 ›› Issue (12): 1950-1957.DOI: 10.1016/S1872-2067(11)60470-1

Solvent-Free Selective Cross-Aldol Condensation of Ketones with Aromatic Aldehydes Efficiently Catalyzed by a Reusable Supported Acidic Ionic Liquid

Abolghasem DAVOODNIA*, Ghazaleh YASSAGHI

Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, Iran

收稿日期:2012-08-15 修回日期:2012-10-23 出版日期:2013-01-18 发布日期:2012-12-18

Solvent-Free Selective Cross-Aldol Condensation of Ketones with Aromatic Aldehydes Efficiently Catalyzed by a Reusable Supported Acidic Ionic Liquid

Abolghasem DAVOODNIA*, Ghazaleh YASSAGHI

Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, Iran

Received:2012-08-15 Revised:2012-10-23 Online:2013-01-18 Published:2012-12-18

摘要/Abstract

摘要： A newly prepared catalyst consisting of acidic ionic liquid 1-(4-sulfonic acid)butylpyridinium hydrogen sulfate supported on silica was used to catalyze the cross-aldol condensation of ketones with aromatic aldehydes under solvent-free conditions. The highly active and selective catalyst gave good to excellent yields of the desired cross-aldol products without the occurrence of any self-condensation reactions. Reaction times were short, the procedure and work-up were simple, and no volatile or hazardous organic solvents were necessary. Moreover, the catalyst could be reused at least four times with only a slight reduction in activity.

关键词: cross-aldol condensation, solvent-free condition, supported acidic ionic liquid, ketone, aromatic aldehyde

Abstract: A newly prepared catalyst consisting of acidic ionic liquid 1-(4-sulfonic acid)butylpyridinium hydrogen sulfate supported on silica was used to catalyze the cross-aldol condensation of ketones with aromatic aldehydes under solvent-free conditions. The highly active and selective catalyst gave good to excellent yields of the desired cross-aldol products without the occurrence of any self-condensation reactions. Reaction times were short, the procedure and work-up were simple, and no volatile or hazardous organic solvents were necessary. Moreover, the catalyst could be reused at least four times with only a slight reduction in activity.

Key words: cross-aldol condensation, solvent-free condition, supported acidic ionic liquid, ketone, aromatic aldehyde

Abolghasem DAVOODNIA, Ghazaleh YASSAGHI. Solvent-Free Selective Cross-Aldol Condensation of Ketones with Aromatic Aldehydes Efficiently Catalyzed by a Reusable Supported Acidic Ionic Liquid[J]. 催化学报, 2012, 33(12): 1950-1957.

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Solvent-Free Selective Cross-Aldol Condensation of Ketones with Aromatic Aldehydes Efficiently Catalyzed by a Reusable Supported Acidic Ionic Liquid

Solvent-Free Selective Cross-Aldol Condensation of Ketones with Aromatic Aldehydes Efficiently Catalyzed by a Reusable Supported Acidic Ionic Liquid

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