催化学报 ›› 2013, Vol. 34 ›› Issue (9): 1667-1673.DOI: 10.1016/S1872-2067(12)60620-2

• 研究论文 • 上一篇    下一篇

室温有氧条件下高稳定性Pd(P-Phos)Cl2配合物催化Suzuki-Miyaura交叉偶联反应

葛轶岑, 程雨晶, 付海燕, 郑学丽, 李瑞祥, 陈华, 李贤均   

  1. 四川大学化学学院教育部绿色化学重点实验室, 四川成都 610064
  • 收稿日期:2013-04-20 修回日期:2013-05-20 出版日期:2013-09-16 发布日期:2013-08-28
  • 通讯作者: 付海燕, 陈华
  • 基金资助:

    国家自然科学基金(21202104).

Suzuki-Miyaura cross-coupling reaction catalyzed by a highly stable Pd(P-Phos)Cl2 complex at room temperature under air

Yicen Ge, Yujing Cheng, Haiyan Fu, Xueli Zheng, Ruixiang Li, Hua Chen, Xianjun Li   

  1. Key Laboratory of Green Chemistry and Technology Ministry of Education; College of Chemistry, Sichuan University, Chengdu 610064, Sichuan, China
  • Received:2013-04-20 Revised:2013-05-20 Online:2013-09-16 Published:2013-08-28
  • Supported by:

    This work was supported by the National Natural Science Foundation of China (21202104).

摘要:

制备了新型Pd(P-Phos)Cl2配合物, 并通过1H, 13C和31P核磁共振及X射线单晶衍射对其结构进行了确认及表征. 结果表明, 该配合物是室温有氧条件下Suzuki-Miyaura交叉偶联反应的高稳定高效催化剂, 并具有广泛的底物适用性. 催化剂用量较低, 且转化数(TON)最高可达49000.

关键词: 钯配合物, 联吡啶双膦配体P-Phos, Suzuki-Miyaura交叉偶联反应, 室温, 空气

Abstract:

A new Pd(P-Phos)Cl2 complex was synthesized and characterized by 1H NMR, 13C NMR, 31P NMR, and X-ray single crystal structure determination. The complex proved to be a highly stable and efficient catalyst for substrates with a wide range of functional groups in Suzuki-Miyaura cross-coupling reactions under air at room temperature. Low catalyst loadings were employed and turnover number of up to 49000 was obtained.

Key words: Palladium complex, P-Phos, Suzuki-Miyaura cross-coupling reaction, Room temperature, Air