催化学报

催化学报 ›› 2014, Vol. 35 ›› Issue (4): 501-508.DOI: 10.1016/S1872-2067(14)60019-X

• 研究论文 • 上一篇    下一篇

A voltammetric sensor with a multiwall carbon nanotube paste electrode and naphthol green as a mediator for the determination of N-actylcysteine in the presence of tryptophan

Mohsen Keyvanfarda, Maryam Tahmasbib, Hassan Karimi-Malehc, Khadijeh Alizada   

  1. a Department of chemistry, Majlesi Branch, Islamic Azad University, Isfahan, Iran;
    b Department of chemistry, Shahreza Branch, Islamic Azad University, Shahreza, Iran;
    c Department of Chemistry, Graduate University of Advanced Technology, Kerman, Iran
  • 收稿日期:2013-11-17 修回日期:2013-12-27 出版日期:2014-03-20 发布日期:2014-03-21
  • 通讯作者: Mohsen Keyvanfard，Hassan Karimi-Maleh

A voltammetric sensor with a multiwall carbon nanotube paste electrode and naphthol green as a mediator for the determination of N-actylcysteine in the presence of tryptophan

Mohsen Keyvanfarda, Maryam Tahmasbib, Hassan Karimi-Malehc, Khadijeh Alizada   

  1. a Department of chemistry, Majlesi Branch, Islamic Azad University, Isfahan, Iran;
    b Department of chemistry, Shahreza Branch, Islamic Azad University, Shahreza, Iran;
    c Department of Chemistry, Graduate University of Advanced Technology, Kerman, Iran
  • Received:2013-11-17 Revised:2013-12-27 Online:2014-03-20 Published:2014-03-21
  • Contact: Mohsen Keyvanfard，Hassan Karimi-Maleh

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摘要：

A multiwall carbon nanotube modified electrode prepared by incorporating multiwall carbon nanotubes in the electrode of a sensor and naphthol green as a homogeneous mediator was used as a voltammetric sensor for the determination of N-actylcysteine (N-AC) in the presence of tryptophan (Trp). The voltammograms of differential pulse voltammetry of N-AC in a mixture with Trp were separated from each other by a potential difference of 200 mV, which allowed the determination of both N-AC and Trp simultaneously. Under the optimum conditions, the electrocatalytic currents increased linearly with N-AC concentration in the range of 0.25-400 μmol/L (two linear segments with different slopes). The detection limit for N-AC was 0.08 μmol/L. The kinetic parameters of the system were determined using electrochemical methods. The method was applied for the determination of N-AC in drug and urine samples.

关键词: N-actylcysteine, Tryptophan, Multiwall carbon nanotube, Naphthol green, Sensor

Abstract:

A multiwall carbon nanotube modified electrode prepared by incorporating multiwall carbon nanotubes in the electrode of a sensor and naphthol green as a homogeneous mediator was used as a voltammetric sensor for the determination of N-actylcysteine (N-AC) in the presence of tryptophan (Trp). The voltammograms of differential pulse voltammetry of N-AC in a mixture with Trp were separated from each other by a potential difference of 200 mV, which allowed the determination of both N-AC and Trp simultaneously. Under the optimum conditions, the electrocatalytic currents increased linearly with N-AC concentration in the range of 0.25-400 μmol/L (two linear segments with different slopes). The detection limit for N-AC was 0.08 μmol/L. The kinetic parameters of the system were determined using electrochemical methods. The method was applied for the determination of N-AC in drug and urine samples.

Key words: N-actylcysteine, Tryptophan, Multiwall carbon nanotube, Naphthol green, Sensor